Beta-diketone hydrolase

In enzymology, a beta-diketone hydrolase is an enzyme that catalyzes the chemical reaction


 * nonane-4,6-dione + H2O $$\rightleftharpoons$$ pentan-2-one + butanoate

Thus, the two substrates of this enzyme are nonane-4,6-dione and H2O, whereas its two products are 2-pentanone and butanoate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is nonane-4,6-dione acylhydrolase. This enzyme is also called oxidized PVA hydrolase.

Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.