Beta-phosphoglucomutase

In enzymology, a β-phosphoglucomutase is an enzyme that catalyzes the chemical reaction


 * β-D-glucose 1-phosphate $$\rightleftharpoons$$ β-D-glucose 6-phosphate

Hence, this enzyme has one substrate, β-D-glucose 1-phosphate, and one product, β-D-glucose 6-phosphate.

This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is beta-D-glucose 1,6-phosphomutase. This enzyme participates in starch and sucrose metabolism.

Structural studies
20 structures have been solved for this enzyme PDB. Some of the accession codes are, , , , , and. Most of these structures detail metal fluoride analogue complexes which are used to mimic different states along the reaction coordinate.