Big Up

Big Up may refer to:


 * Big Up (group), a Black gay men's group that merged with GMFA
 * "Big Up" (Shaggy song), a song by Shaggy
 * "Big Up" (Avalon song), 2005 song by Swedish duo group Avalon
 * Big Ups (band), American musical band
 * Big UP Productions, American film production company
 * The Big Up Festival, a festival of music, art and culture in Ghent, New York