Blue River virus

Blue River virus (BRV) is a single-stranded, negative sense RNA virus of New World hantavirus isolated from a white-footed mouse (Peromyscus leucopus) near the Blue River in Jackson County, Missouri in 1995. Its genome is similar to Sin Nombre orthohantavirus (SNV) but varies in the S1 and S2 segments. Like Sin Nombre orthohantavirus, Blue River virus causes Hantavirus pulmonary syndrome (HPS) in humans.

Natural reservoir
As with all hantavirus species and their reservoirs, Blue River virus is unique to the white-footed mouse.

Transmission
As has been shown with other hantaviruses, transmission is through droplet respiration when rodent excreta becomes aerosolized. Blue River virus has not been shown to transfer via person-to-person.