Brandywine Creek

Brandywine Creek may refer to:

Canada

 * Brandywine Creek (British Columbia), a tributary of the Cheakamus River

United States

 * Brandywine Creek (Big Blue River), in Indiana
 * Brandywine Creek (St. Joseph River tributary), in Michigan
 * Brandywine Creek (Broken Sword Creek tributary), Crawford County, Ohio
 * Brandywine Creek (Cuyahoga River tributary), in Summit County, Ohio
 * Brandywine Creek (Quittapahilla Creek tributary), in Lebanon County, Pennsylvania
 * Brandywine Creek (Christina River tributary), in Chester County, Pennsylvania and New Castle County, Delaware
 * East Branch Brandywine Creek, in Chester County, Pennsylvania
 * West Branch Brandywine Creek, in Chester County, Pennsylvania
 * Brandywine Creek State Park, in New Castle County, Delaware
 * Battle of Brandywine Creek, during the American Revolutionary War (1777)