Brian Duffy

Brian Duffy may refer to:
 * Brian Duffy (astronaut) (born 1953), American astronaut
 * Brian Duffy (chef), celebrity chef
 * Brian Duffy (photographer) (1933–2010), English photographer
 * Brian John Duffy better known as Jet Black (1938–2022), drummer for The Stranglers
 * Brian Duffy (actor), Scottish actor, writer, and artist
 * Brian Duffy (weightlifter), New Zealand weightlifter