Burkholder-O'Keefe House

Burkholder-O'Keefe House is a historic home located at Moberly, Randolph County, Missouri. It was built in 1872, and is a two-story, Italianate style frame I-house. It features a two-story front porch with gable roof. It is one of the oldest surviving houses in Moberly.

It was listed on the National Register of Historic Places in 1989.