C. Granville Wyche House

C. Granville Wyche House is a historic home located at Greenville, South Carolina. It was built in 1931, and consists of a two-story, five bay central blocked flanked by one-story balconied projections. It is of blond brick in the Italian Renaissance style with a low-pitched tile roof, wide eaves with brackets, and full-length, first floor windows. It features a massive portico with grouped classical columns and pilasters. Also on the property is a small grotto and an unpainted barn dating from the mid-1930s.

It was added to the National Register of Historic Places in 1993.