C57

C57 may refer to:
 * ARM Cadete Fernando Montes de Oca, an Admirable-class minesweeper of the Mexican Navy
 * Caldwell 57, a barred irregular galaxy
 * C57BL/6, a common inbred strain of lab mouse
 * Fried Liver Attack, a chess opening
 * HMS Cumberland (C57), a County-class heavy cruiser of the Royal Navy
 * Hours of Work and Manning (Sea) Convention, 1936 of the International
 * JNR Class C57, a class of Japanese 4-6-2 "Pacific" type steam locomotive
 * Lockheed C-57 Lodestar, an American military aircraft