C59

C59 may refer to:
 * ARM Cadete Francisco Márquez, an Admirable-class minesweeper of the Mexican Navy
 * Caldwell 59, a planetary nebula
 * Caudron C.59, a French, two-seat biplane
 * HMS Newfoundland (C59), a Fiji-class light cruiser of the Royal Navy
 * JNR Class C59, a Japanese steam locomotive
 * Lake Lawn Airport (FAA LID: C59), in Walworth County, Wisconsin
 * Lockheed C-59 Lodestar, an American military aircraft
 * Minimum Age (Industry) Convention (Revised), 1937 (ILO code C59), of the International Labour Organization
 * Two Knights Defense (ECO: C59), a chess opening
 * PSLV-C59, ISRO'S PSLV's 59th mission