C65

C65 or C-65 may refer to:
 * Autovía C-65, a road in Catalonia, Spain
 * Berlin Defence (chess), a chess opening
 * Caldwell 65, a spiral galaxy
 * Caudron C.65, a French biplane
 * Commodore 65, a prototype home computer
 * Honda Super Cub, a motorcycle
 * Siemens C65, a mobile phone
 * Stout XC-65, an American experimental aircraft
 * C65, a racing car chassis from Courage Compétition