C80

C80 may refer to :
 * HMS Mauritius (C80), a 1938 British Royal Navy cruiser
 * Final Articles Revision Convention, 1946 code
 * New Coalinga Municipal Airport FAA LID
 * Ruy Lopez chess openings ECO code
 * Malignant neoplasm without specification of site ICD-10 code
 * Caldwell 80 (Omega Centauri or NGC 5139), a globular cluster in the constellation Centaurus
 * C80, carbon-80, a fullerene