CDP-glucose 4,6-dehydratase

The enzyme CDP-glucose 4,6-dehydratase catalyzes the chemical reaction


 * CDP-glucose $$\rightleftharpoons$$ CDP-4-dehydro-6-deoxy- D -glucose + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. This enzyme participates in starch and sucrose metabolism. It employs one cofactor, NAD+.

Nomenclature
The systematic name of this enzyme class is CDP-glucose 4,6-hydro-lyase (CDP-4-dehydro-6-deoxy- D -glucose-forming). Other names in common use include:
 * cytidine diphosphoglucose oxidoreductase, and
 * CDP-glucose 4,6-hydro-lyase.

Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and.