CL2

CL2 may refer to:
 * Chlorine gas, Cl2
 * CAS latency 2, a rating of computer memory
 * Google Calendar, a time-management web application (from a URL fragment used in early versions)
 * Only Built 4 Cuban Linx II, a musical album by American hip-hop artist Raekwon
 * Class 2 rated cables, in the National Electrical Code
 * LPHN2, a human gene that encodes the Latrophilin-2 protein