COF

COF may refer to:


 * Canadian Orienteering Federation, governing body of orienteering in Canada
 * Capital One Financial (NYSE: COF), a United States bank
 * Certificate of Fitness (automotive), may appear on invoice after repair or servicing indicating vehicle is "road ready"
 * Circle of fifths, a concept in music theory
 * Coefficient of friction, the ratio of the force of friction between two bodies and the force pressing them together
 * Cofactor (linear algebra), in linear algebra, cof(A) refers to the sum of the matrix A's
 * Coffin Store, a Finnish subsidiary of Crystal's
 * Congreso Obrero de Filipinas, in the Philippines
 * Cofidis (cycling team), French cycling team
 * Covalent organic framework, two-dimensional and three-dimensional organic solids with extended structures
 * Cradle Of Filth, an English extreme metal band
 * Patrick Space Force Base (IATA: COF), a United States Space Force Base in Florida