CXO

CXO may refer to:


 * Chandra X-ray Observatory, a satellite launched by NASA in 1999
 * Chief experience officer, corporate officer responsible for the overall user experience of an organization
 * CxO (Chief-"x"-officer), also called C-suite, a generic term for any corporate officer
 * CrossOver (software), a commercial version of WINE which runs Windows applications on Linux, Mac OS X and Solaris
 * Lone Star Executive Airport, the airport in Conroe, Texas, United States (IATA code)