Carbazole alkaloids



The carbazole alkaloids are natural products of the indole alkaloid type, derived from carbazole.

Occurrence
Carbazole alkaloids with unsubstituted benzene rings occur rarely. Olivacin has been found in the bark of Aspidosperma olivaceum and ellipticin in Ochrosia elliptica. Some carbazole alkaloids, especially glybomin B, have been isolated from Glycosmis pentaphylla.

Representatives
Representatives include, among others, glycozoline, olivacine and ellipticin and further glybomine B.

Properties
Carbazole alkaloids have cytotoxic and antifungal properties. Furthermore, they have detrimental effects against HIV viruses and tumor cells. Olivacin has fluorescent properties.