Cardinal Piccolomini

Cardinal Piccolomini may refer to:


 * Enea Silvio Piccolomini, cardinal-priest of Santa Sabina from 1456, became Pope Pius II ((r. 1458 – 1464))
 * Francesco Piccolomini, cardinal-deacon of San Eustachio from 1460, became Pope Pius III ((r. undefined – undefined) 1503)
 * Giovanni Piccolomini (1475–1537), cardinal from 1517
 * Celio Piccolomini (1609–1681), cardinal-priest of San Pietro in Montorio from 1664