Category talk:Serotonin releasing agents

79.21.31.13 (talk) 13:41, 15 September 2014 (UTC)

This is intended as a suggestion for investigating hydroxytryptamine potential releasing agents.

I list molecules, which are considered being neither reuptake transporter inhibitors, nor reuptake transporter inverters.

The recursive correspondence between their chemical terminations and their clinical pharmacology is impressive: any carboxyl-R-amine or carboxamide (acetamide) seem behaving in similar way! The model may be possibly generalized comparing the behaviour of any primary amine?

I tried closing my eyes, but the reality made me keep them wide open again...

This is just a sample:

http://www.ncbi.nlm.nih.gov/pubmed/9776325  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1572811/   http://www.ncbi.nlm.nih.gov/pubmed/22735246

http://www.ncbi.nlm.nih.gov/pubmed/21414089

The FDA provides with warnings (about effects which may be explained with a serotonin release model together with ion channels block): http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm100190.htm

I hope someone has the resources to do a systemic linking to the scientific publications; there is already laboratory documentation available.

carboxyl-R-amines

…
 * glycine methionine serine and probably most of the biogenic amino acids or primary amines
 * baclofen gabapentin phenibut pregabalin vigabatrin
 * procaine procainamide

carboxamides


 * atenolol


 * carbamazepines
 * disopyramide
 * felbamate
 * valpromide

…
 * modafinil

79.20.12.96 (talk) 12:27, 17 July 2013 (UTC) 79.45.237.235 (talk) 16:18, 26 July 2013 (UTC) 79.20.12.122 (talk) 16:19, 11 December 2013 (UTC) 79.31.238.217 (talk) 13:40, 14 March 2014 (UTC) 79.31.235.99 (talk) 11:08, 31 March 2014 (UTC) 79.40.235.100 (talk) 09:04, 29 September 2014 (UTC) 79.21.31.44 (talk) 10:51, 2 March 2015 (UTC)