Charles B. Clarke

Charles B. Clarke may refer to:


 * Charles Baron Clarke (1832–1906), British botanist
 * Charles Bailey Clarke (1875–1944), mayor of Portland, Maine, 1918–1921
 * Charles Boss Clarke (1836–1899), designer of the Fagin Building, buried at Bellefontaine Cemetery in St. Louis, Missouri
 * Charles Benjamin Clarke (1844-1891), U.S. Representative from Wisconsin