Charles Byrne

Charles Byrne may refer to:


 * Charles Byrne (giant) (1761–1783), also known as "The Irish Giant"
 * Charles Alfred Byrne (1848–1909), American journalist and playwright
 * Charles C. Byrne (1837–1921), brigadier general in the United States Army
 * Charlie Byrne (Australian footballer) (1895–1924), Australian rules footballer
 * Charlie Byrne (baseball) (1843–1898), original owner of the Brooklyn Dodgers baseball team