Charles Leigh

Charles Leigh may refer to:


 * Charles Leigh (American football) (1945–2006), National Football League running back
 * Charles Leigh (physician) (1662–1701), English physician and naturalist
 * Charles Leigh (British Army officer) (1748–1815), British general
 * Charles Leigh (librarian) (1871–?), English academic librarian
 * Charles Leigh (merchant) (died 1605), English merchant and voyager
 * Charles Leigh (1686–1749), British Member of the UK Parliament for Bedfordshire, Warwick, and Higham Ferrers
 * Charles Leigh (died 1836), British Member of the UK Parliament for New Ross