Charles Osborne

Charles Osborne may refer to:


 * Charles Osborne (politician), MP (1759–1817), Irish politician and judge
 * Sir Charles Osborne, 14th Baronet (1825–1879), Irish baronet of the Osborne baronets
 * Charles Osborne (American football) (ca. 1885 – ? ), American football player and coach
 * Charles Nelson Osborne better known as Uncle Charlie Osborne (1890–1992), American folk musician
 * Charles Osborne (hiccups) (1894–1991), American citizen who suffered from hiccups for 68 years
 * Charles Osborne (music writer) (1927–2017), Australian-born writer on classical music and of Agatha Christie adaptations
 * Chuck Osborne (1939–1979), American professional basketball player
 * Chuck Osborne (American football) (1973–2012), American football player