Charles Sykes

Charles Sykes may refer to:
 * Sir Charles Sykes, 1st Baronet (1868–1950), British wool merchant and politician
 * Charles Robinson Sykes (1875–1950), British sculptor
 * Charles H. Sykes (1881–1966), American member of the Wisconsin State Assembly
 * Charles Henry Sykes (1882–1942), American cartoonist
 * Sir Charles Sykes (metallurgist) (1905–1982), British metallurgist, President of the Physical Society
 * Charlie Sykes (born 1954), American talk radio host and political commentator