ChemDraw

ChemDraw is a molecule editor first developed in 1985 by Selena "Sally" Evans, her husband David A. Evans, and Stewart Rubenstein (later by the cheminformatics company CambridgeSoft). The company was sold to PerkinElmer in 2011. ChemDraw, along with Chem3D and ChemFinder, is part of the ChemOffice suite of programs and is available for Macintosh and Microsoft Windows.

Features of ChemDraw 12.0

 * Chemical structure to name conversion
 * Chemical name to structure conversion
 * NMR spectrum simulation (1H and 13C)
 * Mass spectrum simulation
 * Structure cleanup
 * Draw ligand Structure
 * An extensive collection of templates, including style templates for most major chemical journals.
 * Export to SVG
 * Export to PDF (Mac Version only)

File format
The native file formats for ChemDraw are the binary CDX and the preferred XML-based CDXML formats. ChemDraw can also import from, and export to, MOL, SDF, and SKC chemical file formats.

Plugins
SDK for ChemDraw enables third-party developers to write plugins. For example, Quick HotKey helps to set up HotKeys in interactive mode instead of manually editing the text file.

The plugin website  appears to have been abandoned, and redirects to Revvity Signals' website.