Chesapeake and Ohio Depot

Chesapeake and Ohio Depot may refer to:


 * Ashland, Kentucky station (Chesapeake and Ohio Railway)
 * Chesapeake and Ohio Depot (Catlettsburg, Kentucky)
 * Charleston, West Virginia (Amtrak station)
 * Charlottesville station (Chesapeake and Ohio Railway)
 * Clifton Forge (Amtrak station), Virginia
 * Culpeper (Amtrak station)
 * Hinton (Amtrak station), West Virginia
 * Lee Hall Depot, Newport News, Virginia
 * Chesapeake and Ohio Depot (Marlinton, West Virginia)
 * Maysville (Amtrak station), Kentucky
 * Chesapeake and Ohio Depot (Mount Sterling, Kentucky)
 * Chesapeake and Ohio Depot (Petoskey, Michigan)
 * Chesapeake and Ohio Depot (Pikeville, Kentucky)
 * Prince (Amtrak station), West Virginia
 * Chesapeake and Ohio Depot (St. Albans, West Virginia)
 * Thurmond (Amtrak station), West Virginia
 * White Sulphur Springs (Amtrak station), West Virginia