Chillicothe High School (disambiguation)

Chillicothe High School may refer to:


 * Chillicothe High School, Chillicothe, Ohio
 * Illinois Valley Central High School (formerly Chillicothe High School) in Chillicothe, Illinois
 * Chillicothe High School located in Chillicothe, Missouri
 * Chillicothe High School (Texas), Chillicothe, Texas