Chromosome 21 (TV series)

Chromosome 21 (Cromosoma 21) is a Chilean crime thriller television series co-created by Matías Venables and Nico Martínez Bergen. The series traces a police investigation into a young man with down syndrome involved in a murder. It had its original run on Chilean network Canal 13 on 14 October 2022. Netflix then acquired global streaming rights, and released it on their platform on 8 February 2023. The series received four nominations at the 7th Caleuche Awards, with Sebastián Solorza winning the breakthrough actor award, and five nominations for the 10th Platino Awards.

Main

 * Sebastián Solorza as Tomás "Tomy" Ruiz: a young man with down syndrome who becomes involved in a crime because of his brother
 * Valentina Muhr as Mariana Enríquez: the commissioner of the homicide brigade of the Investigations Police of Chile (PDI)
 * Mario Horton as Bruno Durán: the deputy commissioner of the homicide brigade
 * Gastón Salgado as Guillermo "Bekam" Ruiz: Tomy's younger brother
 * Claudia di Girolamo as Sofía Lombardi: the director of the "Down Up Foundation" and Cristina's mother
 * Pía Urrutia as Cristina Pérez: Sofía's daughter and Tomy's fiancée with down syndrome
 * Daniel Muñoz as Ariel "Coya" Zavala: a former Carabinero who owns the factory where the murder occurred
 * Alejandro Trejo as Rafael Santoro, PDI subprefect; Enríquez and Durán's boss

Production
The series was originally meant to tell the story of a 42-year-old nurse who finds out she is pregnant with a baby with down syndrome, and received a 359230053 CLP grant for it from the National Television Council. Filming took place in Santiago and began on 27 September 2021.