Citramalic acid

Citramalic acid is the organic compound with the formula HO2CCH2C(CH3)(OH)CO2H. A chiral compound, it is related structurally to malic acid.

Synthesis and reactions
Citramalic acid is the hydrated derivative of mesaconic acid, The hydration is catalyzed by mesaconyl-C4-CoA hydratase:
 * HO2CCH=C(CH3)CO2H +  H2O  →   HO2CCH2C(CH3)(OH)CO2H

The same conversion can be achieved in vitro.

The enzyme (S)-citramalyl-CoA lyase converts citramalyl-CoA to acetyl-CoA and pyruvate.