Class 16

Class 16 may refer to:
 * Belgian Railways Class 16
 * British Rail Class 16
 * DRG Class 16, a class of German six-coupled, express train, steam locomotives operated by the Deutsche Reichsbahn which included the:
 * Class 16.0: the Oldenburg S 10
 * Class 16.0II: the BBÖ 310, PKP Class Pn12 and PKP Class Pn11
 * DRG Class E 16
 * LSWR G16 class
 * LSWR H16 class
 * Pennsylvania Railroad class D16
 * Rhodesia Railways 16A class
 * South African Class NG G16 2-6-2+2-6-2
 * VR Class Dr16