Class 350

Class 350 may refer to:


 * British Rail Class 350, a class of electric multiple-unit passenger trains built by Siemens
 * Renfe Class 350, a series of single-cabin diesel locomotives in Spain built in the U.S. by the American Car and Foundry company
 * Talgo 350, a Spanish high-speed train
 * South Australian Railways 350 class, two diesel-electric locomotives built by the Islington Railway Workshops