Cobalt-precorrin-5B (C1)-methyltransferase

Cobalt-precorrin-5B (C1)-methyltransferase, cobalt-precorrin-6A synthase, CbiD (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:cobalt-precorrin-5B (C1)-methyltransferase. This enzyme catalyses the following chemical reaction


 * cobalt-precorrin-5B + S-adenosyl-L-methionine $$\rightleftharpoons$$ cobalt-precorrin-6A + S-adenosyl-L-homocysteine

This enzyme catalyses the C-1 methylation of cobalt-precorrin-5B in the anaerobic pathway of adenosylcobalamin biosynthesis in bacteria such as Salmonella typhimurium, Bacillus megaterium, and Propionibacterium freudenreichii subsp. shermanii.