Codeine 3-O-demethylase

Codeine 3-O-demethylase (, codeine O-demethylase, CODM) is an enzyme with systematic name codeine,2-oxoglutarate:oxygen oxidoreductase (3-O-demethylating). This enzyme catalyses the following chemical reaction


 * codeine + 2-oxoglutarate + O2 $$\rightleftharpoons$$ morphine + formaldehyde + succinate + CO2

Codeine 3-O-demethylase contains Fe2+.