Conserved oligomeric Golgi complex

The conserved oligomeric Golgi complex (COG) is a multiprotein complex found in the Golgi apparatus structure and involved in intracellular transport and glycoprotein modification.

Earlier names for this complex were: the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and are termed the conserved oligomeric Golgi (COG) complex.

Structure
The COG protein complex consists of eight subunits, in two lobes; Lobe A consists of COG1, COG2, COG3, COG4 and lobe B consists of COG5, COG6, COG7, COG8.

Function
The conserved oligomeric Golgi complex plays important roles in maintaining structure and transport mechanisms within the Golgi apparatus.