D-alanine—D-serine ligase

 D -Alanine— D -serine ligase (, VanC, VanE, VanG) is an enzyme with systematic name D-alanine:D-serine ligase (ADP-forming). This enzyme catalyses the following chemical reaction


 * D -alanine + D -serine + ATP $$\rightleftharpoons$$ D -alanyl- D -serine + ADP + phosphate

The product of this enzyme, D-alanyl-D-serine, can be incorporated into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-alanine dipeptide.