D-serine ammonia-lyase

The enzyme  D -serine ammonia-lyase (EC 4.3.1.18), with systematic name  D -serine ammonia-lyase (pyruvate-forming), catalyzes the chemical reaction


 * D -serine = pyruvate + NH3 (overall reaction)
 * (1a) D -serine = 2-aminoprop-2-enoate + H2O
 * (1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous)
 * (1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous

Other names in common use include  D -hydroxyaminoacid dehydratase,  D -serine dehydrase,  D -hydroxy amino acid dehydratase,  D -serine hydrolase,  D -serine dehydratase (deaminating),  D -serine deaminase, and  D -serine hydro-lyase (deaminating). This enzyme participates in glycine, serine and threonine metabolism. It employs one cofactor, pyridoxal phosphate.