DE16

DE16 may refer to:
 * ARC Boyaca (DE-16), a Columbia navy ship purchased from the U.S. Navy in 1972, originally launched in 1956 as USS Hartley (DE-1029)
 * Delaware Route 16
 * USS Edgar G. Chase (DE-16), a U.S. Navy ship launched 1942, decommissioned 1945, scrapped 1947