DRE

DRE may refer to:


 * Dre (album), 2010 by American rapper Soulja Boy Tell 'Em, 2010
 * Dre (given name)
 * Dr. Dre, American rapper and producer
 * DRE voting machine
 * Digital rectal examination, in medicine
 * Director of religious education; for example,
 * Directorio Revolucionario Estudiantil, CIA backed anti-Castro group based in Miami
 * Drug Recognition Expert, law enforcement
 * Drug resistant epilepsy, in neurology
 * Dense-rock equivalent, in geology/volcanology