DS

DS may refer to:

Video games

 * Nintendo DS, handheld game console
 * Deca Sports, a sports video game series
 * Deca Sports (video game), the first game of the series
 * Double Spoiler, a game in the Touhou Project series
 * Dark Souls, a series of action role-playing games
 * Dark Souls (video game), the first game in the series
 * Death Stranding, an action game
 * Don't Starve, a survival game

Music

 * "D.S." (song), a 1995 song by Michael Jackson
 * Dal segno (D.S.), a navigation marker in music notation

Organisations

 * Committee for State Security (Bulgaria), a former Bulgarian secret service
 * Democratici di Sinistra (Democrats of the Left), a former Italian political party
 * Democratic Party (Demokratska stranka), a political party in Serbia
 * Bureau of Diplomatic Security, in the US Department of State

Science and technology

 * Dwarf spiral galaxy (dS)
 * Darmstadtium (symbol Ds), a chemical element
 * Data science
 * Degree of substitution, relative density of substituent groups in a polymer
 * Dielectric spectroscopy, measuring dielectric properties of medium
 * Directional symmetry (time series)
 * Dnepropetrovsk Sputnik, a class of Soviet satellites

Computing

 * DS register, of X86 processor
 * Avid DS, defunct editing and effects software
 * Delegation Signer, DNSSEC record type
 * DirectShow, Microsoft API
 * Nintendo DS

Mathematics

 * ds (elliptic function), one of Jacobi's elliptic functions
 * De Sitter space (dS)

Medicine

 * Down syndrome, a genetic disorder
 * Duodenal switch, a weight-loss surgery

Transportation

 * DS Automobiles, a French car marque
 * Citroën DS Inside (2009), a concept car
 * Citroën DS (1955-1975), a car model
 * EasyJet Switzerland (IATA code: DS), an airline

Weapons

 * 7.92 DS, a Polish-designed anti-tank ammunition type
 * DS-39, Degtyaryova Stankovyi Model 1939, a Russian medium machine gun

Other uses

 * Detective Sergeant, UK police rank
 * Detective Superintendent, UK and Australian police rank
 * Diodorus Siculus (D.S. or DS), a first-century BCE Greek historian
 * Dominance and submission (D/s), a set of behaviors
 * Enchiridion symbolorum, definitionum et declarationum de rebus fidei et morum ("Denzinger-Schönmetzer", DS), a book of Catholic dogma
 * Different subject, in switch-reference