DS1

DS1 or DS-1 may refer to:
 * BOSS DS-1, a guitar distortion pedal
 * Digital Signal 1, a T-carrier signaling scheme devised by Bell Labs
 * Deep Space 1, a mission to 9969 Braille & 19P/Borrelly
 * DS-1 (drug), a selective GABAA α4β3δ agonist drug
 * South African Class DS1, a diesel locomotive class
 * Datsun DS-1, a car by Nissan, see Datsun DS Series
 * Dark Souls, an action role-playing game
 * Dead Space (2008 video game), a survival horror game
 * VR Class Ds1, a Finnish railbus class
 * DS-1 Orbital Battle Station, the full name of the original Death Star space station in the Star Wars franchise