David Grimes

David Grimes may refer to:
 * David Grimes (American football) (born 1986), American football wide receiver
 * David Grimes (composer) (born 1948), American composer
 * David Grimes (physician) (born 1947), American physician and abortion provider
 * David Robert Grimes (born 1985), physicist and cancer researcher at the University of Oxford
 * David Grimes (meteorologist), Canadian meteorologist