De Witt (CDP), New York

De Witt is a census-designated place (CDP) in the town of DeWitt, Onondaga County, New York, United States. It was first listed as a CDP prior to the 2020 census.

The CDP is in eastern Onondaga County, in the southern part of the town of DeWitt. It is bordered to the northwest by the city of Syracuse, to the north by the village of East Syracuse, and to the east and south by Interstate 481, which separates it from the rest of the town of DeWitt. East Genesee Street is the main road through the CDP, leading west 4 mi to downtown Syracuse and east 3 mi to Fayetteville. New York State Route 92 follows East Genesee Street within the De Witt CDP, while State Route 5 follows it in the eastern part of the CDP, before turning north to take Erie Boulevard toward downtown.

Le Moyne College is in the northwest corner of the CDP.