Desc

Desc or DESC may refer to:


 * Descent
 * Bernard Descoings (1931–2018), in botanist author citations (Desc.)
 * Downtown Emergency Service Center, a non-profit organization serving the homeless community in Seattle
 * Defense Electronics Supply Center, a former base now in the Defense Supply Center, Columbus
 * Diplôme d'Etudes Spécialisées Complémentaires, a degree in the French medical system