Despair (disambiguation)

Despair is a state of depressed mood and hopelessness.

Despair may also refer to:
 * Despair (sculpture), a c. 1890 sculpture by Auguste Rodin
 * Despair (novel), a 1936 novel by Vladimir Nabokov
 * Despair (film), a 1978 film adaptation by Rainer Fassbinder
 * Despair (band), a thrash metal band
 * Despair (DC Comics), a character in the Sandman comic book series
 * Despair (album), an album by Omar Rodríguez-López
 * Despair, Inc., a company that makes satirical posters and souvenirs
 * Mount Despair (Washington), a mountain in the North Cascades National Park
 * Giant Despair, a character in The Pilgrim's Progress by John Bunyan
 * Despair, a 1969 underground comic by Robert Crumb
 * "Despair", a song by the Yeah Yeah Yeahs from their studio album Mosquito, 2013
 * Neka mi ne svane, Croatian Eurovision Song Contest entry from 1998, also known as "Despair".