Desu

Desu or DESU may refer to:


 * Desu (Japanese: です), the polite form of the Japanese copula often translated as "to be"
 * Suiseiseki, a character from the anime and manga series Rozen Maiden whose overusage and unusual pronunciation of the copula became an early Internet meme
 * Adalbert Deșu (Béla Dezső, 1909–1937), a Romanian football striker
 * Delaware State University, sometimes abbreviated as DESU
 * Diplôme d'études supérieures universitaires (DESU), a French academic grade