Diacylglycerol cholinephosphotransferase

In enzymology, a diacylglycerol cholinephosphotransferase is an enzyme that catalyzes the chemical reaction



CDP-choline + 1,2-diacylglycerol $$\rightleftharpoons$$ CMP + a phosphatidylcholine

Thus, the two substrates of this enzyme are CDP-choline and 1,2-diacylglycerol, whereas its two products are CMP and phosphatidylcholine.

Classification
This enzyme belongs to the family of transferases, specifically those transferring non-standard substituted phosphate groups.

Nomenclature
The systematic name of this enzyme class is CDP choline:1,2-diacylglycerol cholinephosphotransferase. Other names in common use include:


 * 1-alkyl-2-acetyl-m-glycerol:CDPcholine choline phosphotransferase,
 * 1-alkyl-2-acetyl-sn-glycerol cholinephosphotransferase,
 * 1-alkyl-2-acetylglycerol cholinephosphotransferase,
 * alkylacylglycerol choline phosphotransferase,
 * alkylacylglycerol cholinephosphotransferase,
 * CDP-choline diglyceride phosphotransferase,
 * cholinephosphotransferase,
 * CPT,
 * cytidine diphosphocholine glyceride transferase,
 * cytidine diphosphorylcholine diglyceride transferase,
 * diacylglycerol choline phosphotransferase,
 * phosphocholine diacylglyceroltransferase,
 * phosphorylcholine-glyceride transferase, and
 * sn-1,2-diacylglycerol cholinephosphotransferase.

Biological role
This enzyme participates in 3 metabolic pathways: aminophosphonate metabolism, glycerophospholipid metabolism, and ether lipid metabolism.