Diadenosine hexaphosphate hydrolase (AMP-forming)

Diadenosine hexaphosphate hydrolase (AMP-forming) (, hAps1, NUDT11 (gene), hAps2, NUDT10 (gene)) is an enzyme with systematic name P1,P6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (AMP-forming). This enzyme catalyses the following chemical reaction


 * (1) P1,P6-bis(5'-adenosyl)hexaphosphate + H2O $$\rightleftharpoons$$ adenosine 5'-pentaphosphate + AMP
 * (2) P1,P5-bis(5'-adenosyl)pentaphosphate + H2O $$\rightleftharpoons$$ adenosine 5'-tetraphosphate + AMP

A divalent cation is essential for activity.