Diadenosine hexaphosphate hydrolase (ATP-forming)

Diadenosine hexaphosphate hydrolase (ATP-forming) (, Ndx1) is an enzyme with systematic name P1,P6-bis(5'-adenosyl)hexaphosphate nucleotidohydrolase (ATP-forming). This enzyme catalyses the following chemical reaction


 * (1) P1,P6-bis(5'-adenosyl)hexaphosphate + H2O $$\rightleftharpoons$$ 2 ATP
 * (2) P1,P5-bis(5'-adenosyl)pentaphosphate + H2O $$\rightleftharpoons$$ ATP + ADP
 * (3) P1,P4-bis(5'-adenosyl)tetraphosphate + H2O $$\rightleftharpoons$$ ATP + AMP

The enzyme requires the presence of the divalent cations (Mn2+, Mg2+, Zn2+, and Co2+).