Domestic Science Building

Domestic Science Building may refer to:


 * Domestic Science Building (Normal, Alabama), listed on the National Register of Historic Places in Madison County, Alabama
 * Domestic Science Building (Arkadelphia, Arkansas), NRHP-listed
 * Girls' Domestic Science and Arts Building, Russellville, Arkansas, NRHP-listed
 * Domestic Science and Manual Training School, St. Petersburg, Florida, NRHP-listed