Draft:Amelogen

ACP4(Acid Phosphatase 4) is a protein that in humans is encoded by ACP4 gene.

[Function]
ACP4 is involved in biomineralization during tooth enamel development.

[Clinical Significance]
Mutations in ACP4 result in amelogenesis imperfecta. It has been shown that mice with a knocked-out ACP4 gene will present disorganized and hypoplastic enamel.